Trastornos de Diferenciación Sexual

	Arch Dis Child. 2004 May;89(5):401-7. Early assessment of ambiguous genitalia. Ogilvy-Stuart AL, Brain CE. Neonatal Unit, Rosie Hospital, Addenbrooke's NHS Trust, Cambridge CB2 2SW, UK. amanda.ogilvy-stuart@addenbrookes.nhs.uk To discover that there is uncertainty about the sex of one’s newborn baby is devastating and often incomprehensible for most parents. It is paramount that clear explanations and investigations are commenced promptly, and that no attempt is made to guess the sex of the baby. Extreme sensitivity is required, and ideally the baby should be managed in a tertiary centre by a multidisciplinary team including a paediatric endocrinologist and a paediatric urologist. Early involvement of a clinical psychologist with experience in this field should be mandatory. Other professionals including geneticists and gynaecologists may also become involved. There must be access to specialist laboratory facilities and experienced radiologists. The incidence of genital ambiguity that results in the child’s sex being uncertain is 1 per 4500,1although some degree of male undervirilisation, or female virilisation may be present in as many as 2% of live births PMCID: PMC1719899
	PMID: 15102623 [PubMed - indexed for MEDLINE]
	MeSH Terms: DNA/analysis, Genitalia/abnormalities, Gonadal Steroid Hormones/physiology, Infant, Newborn, Physical Examination, Sex Differentiation Disorders/diagnosis*