En niño con infección recurrente

	Clin Exp Immunol. 2008 Jun;152(3):389-96. Epub 2008 Mar 28. Clinical immunology review series: an approach to the patient with recurrent infections in childhood. Slatter MA, Gennery AR. Department of Paediatric Immunology, Newcastle upon Tyne Hospitals Foundation Trust, Newcastle upon Tyne, UK. Abstract Recurrent or persistent infection is the major manifestation of primary immunodeficiency, which also results in atypical infection with opportunistic organisms. Young children are also vulnerable to infection and recurrent infection is common. While most children with recurrent infection have a normal immunity, it is important to recognize the child with an underlying primary immunodeficiency and investigate and treat appropriately and yet not over investigate normal children. Prompt, accurate diagnosis directs the most appropriate treatment, and early and judicious use of prophylactic antibiotics and replacement immunoglobulin can prevent significant end organ damage and improve long-term outlook and quality of life. This paper describes important presenting features of primary immunodeficiency and indicates when further investigation is warranted. PMCID: PMC2453200 Free PMC Article
	PMID: 18373701 [PubMed - indexed for MEDLINE]
	MeSH Terms Immunologic Deficiency Syndromes/complications*, Immunologic Deficiency Syndromes/diagnosis* Opportunistic Infections/complications*, Opportunistic Infections/immunology Opportunistic Infections/therapy, Recurrence