Indicaciones y seguridad de rituximab en enfermedad renal

	Pediatr Nephrol. 2012 Sep 21. [Epub ahead of print] Indications for use and safety of rituximab in childhood renal diseases. Tullus K, Marks SD. Source Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, WC1N 3JH, England, UK, Kjell.Tullus@gosh.nhs.uk. Abstract Rituximab was initially developed for the treatment of patients with B cell lymphoma but has during the last decade proven to be quite effective in treating a range of kidney diseases including lupus nephritis, nephrotic syndrome, and also in different situations before and after a renal transplant. We will here review the scientific basis for the use of rituximab in children with renal diseases and give recommendations both regarding its clinical use and need for further research.
	PMID: 22992983 [PubMed - as supplied by publisher]