Tratamiento de síndrome nefrótico esteroide resistente

	Pediatr Nephrol. 2012 Oct 5. [Epub ahead of print] Treatment of steroid-resistant nephrotic syndrome in children: new guidelines from KDIGO. Lombel RM, Hodson EM, Gipson DS. Source Division of Nephrology, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI, USA, rlombel@med.umich.edu. Abstract Kidney Disease: Improving Global Outcomes (KDIGO) recently published the clinical practice guideline on glomerulonephritis (GN) to assist the practitioner caring for patients with GN. Chapter 4 of the guideline focuses on managing children aged 1-18 years with steroid-resistant nephrotic syndrome (SRNS), defined by an inability to achieve complete remission with corticosteroid therapy. Guideline development followed a thorough evidence review, and management recommendations and suggestions were based on the best available evidence. Limitations of the evidence, including the paucity of large-scale randomized controlled trials, are discussed. This article provides both the guideline recommendations and a brief review of relevant treatment trials related to each recommendation. This précis serves as a summary of the complete guidelines recently published.
	PMID: 23052648 [PubMed - as supplied by publisher]